Scientists evaluate the safety of Jiedu Huayu, a traditional Chinese herbal compound

A study confirmed that Jiedu Huayu, a traditional Chinese herbal medicine, is safe to use orally at dosage levels of less than or equal to 130 g/kg a day. The study, published in the journal BMC Complementary and Alternative Medicine, evaluated the safety of Jiedu Huayu granules.

  • Jiedu Huayu is a traditional Chinese medicine used to treat liver failure, and earlier studies support that it is an effective treatment.
  • Jiedu Huayu granules are composed of six herbs, namely: Capillary wormwood (Artemisia capillaris), peony root (radix paeoniae rubrathe), the Chinese rhubarb (Rheum officinale), snake-needle grass (Oldenlandia diffusa), turmeric root (radix curcumae), and grass-leaf sweet flag (Acorus gramineus).
  • Researchers from The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine in Nanning, Guangxi Province, China assessed the toxicity and safety of an oral administration of Jiedu Huayu to mice.
  • For the study, they orally gave male and female mice Jiedu Huayu at three different doses: 80, 100, and 130 g/kg per day for 13 weeks.
  • During the study, they monitored the clinical signs, body weight, food consumption, hematological and biochemical parameters, organ coefficients, and histological changes.
  • The researchers revealed that the treatment did not cause any side effects on mice at any dose.
  • It did not cause any damaging effect on liver, kidney, and lung function.

Therefore, the researchers concluded that taking Jiedu Huayu granules below or equal to 130 g/kg per day for treating liver failure is safe.

Read the full text of the study at this link.

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Journal Reference:

Wang M, Qiu H, Zhang R, Long F, Mao D. SUBCHRONIC TOXICITY OF HERBAL COMPOUND “JIEDU HUAYU” GRANULES IN RATS. BMC Complementary and Alternative Medicine. 6 September 2017; 17(450). DOI: 10.1186/s12906-017-1960-4

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