False pepperwort leaves found to be effective against urolithiasis (kidney stones)


False pepperwort (Marsilea crenata), also known as water clover, has been used to treat kidney disturbances in various cultures. A study published in the American Journal of Animal and Veterinary Sciences investigates if the herb’s medicinal benefits also extend to dogs.

  • The researcher aimed to determine the potential of false pepperwort leaf and stalk extract as a treatment for urolithiasis or kidney stones in animals.
  • An animal model was created composed of Wistar rats. The animals were divided into six groups: negative control, positive control (treated with 0.75 percent ethylene glycol (EG) and two percent ammonium chloride (AC)); and four groups of preventive control (given 5, 10, 20, and 40 percent M. crenata leaves and stalks juices). The treatment lasted for 10 days.
  • The researcher took note of several indicators: Blood Urea Nitrogen (BUN) and serum creatinine, urine creatinine, and creatinine clearance (Ccr).
  • After the treatment, the author noted reductions in both BUN and Ccr.

The results were interpreted as proof that false pepperwort extracts can help treat kidney issues characteristic of urolithiasis.

Learn about common pet diseases at PetHealth.news.

Journal Reference:

Murwani S. PREVENTIVE EFFECT OF MARSILEACRENATA LEAVES AND STALKS JUICES AGAINST UROLITHIASIS SHOWED BY IMPROVING OF KIDNEY FUNCTION. American Journal of Animal and Veterinary Sciences. 2016;11(1):47–54. DOI: 10.3844/ajavsp.2016.47.54



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